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光線医療センター Center for Photodynamic Medicine

業績一覧

 
インドシアニングリーン(ICG)を用いた近赤外蛍光診断
Cerebral malperfusion in acute aortic dissection. Orihashi K. Surg Today. 2016 Dec;46(12):1353-1361. Epub 2016 Jul 18. Review.
Reconstruction using a divided latissimus dorsi muscle flap after conventional posterolateral thoracotomy and the effectiveness of indocyanine green-fluorescence angiography to assess intraoperative blood flow. Kuriyama M, Yano A, Yoshida Y, Kubo M, Akita S, Mitsukawa N, Satoh K, Yamamoto S, Sasaguri S, Orihashi K. Surg Today. 2016 Mar;46(3):326-34. doi: 10.1007/s00595-015-1181-8. Epub 2015 May 5.
Efficacy of intraoperative HyperEye Medical System angiography for coronary artery bypass grafting. Yamamoto M, Orihashi K, Nishimori H, Handa T, Kondo N, Fukutomi T, Sato T. Surg Today. 2015 Aug;45(8):966-72. doi: 10.1007/s00595-014-1015-0. Epub 2014 Aug 28.
Recent advances in near-infrared fluorescence-guided imaging surgery using indocyanine green. Namikawa T, Sato T, Hanazaki K. Surg Today. 2015;45(12):1467-74.
Visualization of the Stomach's Arterial Networks During Esophageal Surgery Using the HyperEye Medical System. Kitagawa H, Namikawa T, Munekage M, Akimori T, Kobayashi M, Hanazaki K. Anticancer Res. 2015;35(11):6201-5.
Minimally invasive electro-magnetic navigational bronchoscopy-integrated near-infrared-guided sentinel lymph node mapping in the porcine lung. Wada H, Hirohashi K, Anayama T, Nakajima T, Kato T, Chan HH, Qiu J, Daly M, Weersink R, Jaffray DA, Irish JC, Waddell TK, Keshavjee S, Yoshino I, Yasufuku K. PLoS One. 2015 May 20;10(5):e0126945. doi: 10.1371/journal.pone.0126945. eCollection 2015.
Photothermal ablation of human lung cancer by low-power near-infrared laser and topical injection of indocyanine green. Hirohashi K, Anayama T, Wada H, Nakajima T, Kato T, Keshavjee S, Orihashi K, Yasufuku K. J Bronchology Interv Pulmonol. 2015 Apr;22(2):99-106. doi: 10.1097/LBR.0000000000000158.
Localization of pulmonary nodules using navigation bronchoscope and a near-infrared fluorescence thoracoscope. Anayama T, Qiu J, Chan H, Nakajima T, Weersink R, Daly M, McConnell J, Waddell T, Keshavjee S, Jaffray D, Irish JC, Hirohashi K, Wada H, Orihashi K, Yasufuku K. Ann Thorac Surg. 2015 Jan;99(1):224-30. doi: 10.1016/j.athoracsur.2014.07.050. Epub 2014 Nov 6.
Successful preservation of the mesenteric and bowel circulation with treatment for a ruptured superior mesenteric artery aneurysm using the HyperEye Medical System. Namikawa T, Uemura S, Kondo N, Yamamoto M, Maeda H, Nishimori H, Sato T, Orihashi K, Kobayashi M, Hanazaki K. Am Surg. 2014;80(12):E359-61.
Malperfusion in acute type a aortic dissection: unsolved problem. Orihashi K. Ann Thorac Surg. 2013 May;95(5):1570-6. doi: 10.1016/j.athoracsur.2013.02.025. Epub 2013 Apr 3.
Acute type a aortic dissection: for further improvement of outcomes. Orihashi K. Ann Vasc Dis. 2012;5(3):310-20. doi: 10.3400/avd.ra.12.00051.
Indocyanine green angiography for intra-operative assessment in vascular surgery. Yamamoto M, Orihashi K, Nishimori H, Wariishi S, Fukutomi T, Kondo N, Kihara K, Sato T, Sasaguri S. Eur J Vasc Endovasc Surg. 2012 Apr;43(4):426-32. doi: 10.1016/j.ejvs.2011.12.030. Epub 2012 Jan 21.
Treatment strategy for acute type a aortic dissection complicated with organ ischemia. Orihashi K, Ozawa M, Takahashi S, Takasaki T, Sato K, Kurosaki T, Herlambang B, Imai K, Sueda T. Ann Vasc Dis. 2011;4(4):293-8. doi: 10.3400/avd.oa.11.00041. Epub 2011 Sep 29.
Assessing intraoperative blood flow in cardiovascular surgery. Yamamoto M, Sasaguri S, Sato T. Surg Today. 2011 Nov;41(11):1467-74. doi: 10.1007/s00595-010-4553-0. Epub 2011 Oct 4.
Detection and monitoring of complications associated with femoral or axillary arterial cannulation for surgical repair of aortic dissection. Orihashi K, Sueda T, Okada K, Imai K. J Cardiothorac Vasc Anesth. 2006 Feb;20(1):20-5.
Malposition of selective cerebral perfusion catheter is not a rare event. Orihashi K, Sueda T, Okada K, Imai K. Eur J Cardiothorac Surg. 2005 Apr;27(4):644-8.
Perioperative diagnosis of mesenteric ischemia in acute aortic dissection by transesophageal echocardiography. Orihashi K, Sueda T, Okada K, Imai K. Eur J Cardiothorac Surg. 2005 Dec;28(6):871-6. Epub 2005 Nov 7.
Near-infrared spectroscopy for monitoring cerebral ischemia during selective cerebral perfusion. Orihashi K, Sueda T, Okada K, Imai K. Eur J Cardiothorac Surg. 2004 Nov;26(5):907-11.
Reversible visceral ischemia detected by transesophageal echocardiography and near-infrared spectroscopy. Orihashi K, Matsuura Y, Sueda T, Watari M, Okada K. J Thorac Cardiovasc Surg. 2000 Feb;119(2):384-6.
5-アミノレブリン酸(5-ALA)を用いた光線力学診断(PDD)
Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy. Nakayama T, Otsuka S, Kobayashi T, Okajima H, Matsumoto K, Hagiya Y, Inoue K, Shuin T, Nakajima M, Tanaka T, Ogura SI. Sci Rep. 2016 Nov 18;6:36478. doi: 10.1038/srep36478 .
Phytoestrogen Suppresses Efflux of the Diagnostic Marker Protoporphyrin IX in Lung Carcinoma. Fujita H, Nagakawa K, Kobuchi H, Ogino T, Kondo Y, Inoue K, Shuin T, Utsumi T, Utsumi K, Sasaki J, Ohuchi H. Cancer Res. 2016 Apr 1;76(7):1837-46. doi: 10.1158/0008-5472.CAN-15-1484. Epub 2016 Feb 2.
The clinical trial on the safety and effectiveness of the photodynamic diagnosis of non-muscle-invasive bladder cancer using fluorescent light-guided cystoscopy after oral administration of 5-aminolevulinic acid (5-ALA). Inoue K, Matsuyama H, Fujimoto K, Hirao Y, Watanabe H, Ozono S, Oyama M, Ueno M, Sugimura Y, Shiina H, Mimata H, Azuma H, Nagase Y, Matsubara A, Ito YM, Shuin T. Photodiagnosis Photodyn Ther. 2016 Mar;13:91-6. doi: 10.1016/j.pdpdt.2015.12.011. Epub 2016 Jan 2.
The Utility of a Flexible Fluorescence-Cystoscope with a Twin Mode Monitor for the 5-Aminolevulinic Acid-Mediated Photodynamic Diagnosis of Bladder Cancer. Fukuhara H, Kureishi M, Khoda T, Inoue K, Tanaka T, Iketani K, Orita M, Inoue K, Shuin T. PLoS One. 2015 Sep 2;10(9):e0136416. doi: 10.1371/journal.pone.0136416. eCollection 2015.
Clinical applications of 5-aminolevulinic acid-mediated fluorescence for gastric cancer. Namikawa T, Yatabe T, Inoue K, Shuin T, Hanazaki K. World J Gastroenterol. 2015 Aug 7;21(29):8769-75. doi: 10.3748/wjg.v21.i29.8769. Review.
Performance of 5-aminolevulinic-acid-based photodynamic diagnosis for radical prostatectomy. Fukuhara H, Inoue K, Kurabayashi A, Furihata M, Shuin T. BMC Urol. 2015 Aug 1;15:78. doi: 10.1186/s12894-015-0073-y
Plasma protoporphyrin IX following administration of 5-aminolevulinic acid as a potential tumor marker. Ota U, Fukuhara H, Ishizuka M, Abe F, Kawada C, Tamura K, Tanaka T, Inoue K, Ogura SI, Shuin T. Mol Clin Oncol. 2015 Jul;3(4):797-801. Epub 2015 Apr 24.
Oral 5-aminolevulinic acid mediated photodynamic diagnosis using fluorescence cystoscopy for non-muscle-invasive bladder cancer: A randomized, double-blind, multicentre phase II/III study. Inoue K, Anai S, Fujimoto K, Hirao Y, Furuse H, Kai F, Ozono S, Hara T, Matsuyama H, Oyama M, Ueno M, Fukuhara H, Narukawa M, Shuin T. Photodiagnosis Photodyn Ther. 2015 Jun;12(2):193-200. doi: 10.1016/j.pdpdt.2015.03.008. Epub 2015 Apr 2.
The effect of iron ion on the specificity of photodynamic therapy with 5-aminolevulinic acid. Hayashi M, Fukuhara H, Inoue K, Shuin T, Hagiya Y, Nakajima M, Tanaka T, Ogura S. PLoS One. 2015 Mar 30;10(3):e0122351. doi: 10.1371/journal.pone.0122351. eCollection 2015.
Application of 5-aminolevulinic acid-mediated photodynamic diagnosis to robot-assisted laparoscopic radical prostatectomy. Inoue K, Ashida S, Fukuhara H, Iiyama T, Miyamura M, Kurabayashi A, Furihata M, Shuin T. Urology. 2013 Nov;82(5):1175-8.
5-Aminolevulinic acid protects against cisplatin-induced nephrotoxicity without compromising the anticancer efficiency of cisplatin in rats in vitro and in vivo. Terada Y, Inoue K, Matsumoto T, Ishihara M, Hamada K, Shimamura Y, Ogata K, Inoue K, Taniguchi Y, Horino T, Karashima T, Tamura K, Fukuhara H, Fujimoto S, Tsuda M, Shuin T. PLoS One. 2013 Dec 6;8(12):e80850. doi: 10.1371/journal.pone.0080850. eCollection 2013.
Porphyrins as urinary biomarkers for bladder cancer after 5-aminolevulinic acid (ALA) administration: the potential of photodynamic screening for tumors. Inoue K, Ota U, Ishizuka M, Kawada C, Fukuhara H, Shuin T, Okura I, Tanaka T, Ogura S. Photodiagnosis Photodyn Ther. 2013 Dec;10(4):484-9. doi: 10.1016/j.pdpdt.2013.05.002. Epub 2013 Jun 10.
The inhibition of ferrochelatase enhances 5-aminolevulinic acid-based photodynamic action for prostate cancer. Fukuhara H, Inoue K, Kurabayashi A, Furihata M, Fujita H, Utsumi K, Sasaki J, Shuin T. Photodiagnosis Photodyn Ther. 2013 Dec;10(4):399-409. doi: 10.1016/j.pdpdt.2013.03.003. Epub 2013 Apr 12.
Photodynamic diagnosis using 5-aminolevulinic acid during gastrectomy for gastric cancer. Namikawa T, Inoue K, Uemura S, Shiga M, Maeda H, Kitagawa H, Fukuhara H, Kobayashi M, Shuin T, Hanazaki K. J Surg Oncol. 2014 Mar;109(3):213-7. doi: 10.1002/jso.23487. Epub 2013 Nov 8.
Expression levels of PEPT1 and ABCG2 play key roles in 5-aminolevulinic acid (ALA)-induced tumor-specific protoporphyrin IX (PpIX) accumulation in bladder cancer. Hagiya Y, Fukuhara H, Matsumoto K, Endo Y, Nakajima M, Tanaka T, Okura I, Kurabayashi A, Furihata M, Inoue K, Shuin T, Ogura S. Photodiagnosis Photodyn Ther. 2013 Sep;10(3):288-95. doi: 10.1016/j.pdpdt.2013.02.001. Epub 2013 Mar 15.
Photodynamic therapy involves an antiangiogenic mechanism and is enhanced by ferrochelatase inhibitor in urothelial carcinoma. Inoue K, Fukuhara H, Kurabayashi A, Furihata M, Tsuda M, Nagakawa K, Fujita H, Utsumi K, Shuin T. Cancer Sci. 2013 Jun;104(6):765-72. doi: 10.1111/cas.12147. Epub 2013 Apr 17.
Improvement of aminolevulinic acid (ALA)-mediated photodynamic diagnosis using n-propyl gallate. Hirano T, Hagiya Y, Fukuhara H, Inoue K, Shuin T, Matsumoto K, Inoue K, Tanaka T, Okura I, Ogura S. Photodiagnosis Photodyn Ther. 2013 Feb;10(1):28-32. doi: 10.1016/j.pdpdt.2012.06.002. Epub 2012 Jul 17.
Mitochondrial localization of ABC transporter ABCG2 and its function in 5-aminolevulinic acid-mediated protoporphyrin IX accumulation. Kobuchi H, Moriya K, Ogino T, Fujita H, Inoue K, Shuin T, Yasuda T, Utsumi K, Utsumi T. PLoS One. 2012;7(11):e50082. doi: 10.1371/journal.pone.0050082. Epub 2012 Nov 26.
Comparison between intravesical and oral administration of 5-aminolevulinic acid in the clinical benefit of photodynamic diagnosis for nonmuscle invasive bladder cancer. Inoue K, Fukuhara H, Shimamoto T, Kamada M, Iiyama T, Miyamura M, Kurabayashi A, Furihata M, Tanimura M, Watanabe H, Shuin T. Cancer. 2012 Feb 15;118(4):1062-74. doi: 10.1002/cncr.26378. Epub 2011 Jul 19.
Serum-dependent export of protoporphyrin IX by ATP-binding cassette transporter G2 in T24 cells. Ogino T, Kobuchi H, Munetomo K, Fujita H, Yamamoto M, Utsumi T, Inoue K, Shuin T, Sasaki J, Inoue M, Utsumi K. Mol Cell Biochem. 2011 Dec;358(1-2):297-307. doi: 10.1007/s11010-011-0980-5. Epub 2011 Jul 12.
Photodynamic diagnosis of positive margin during radical prostatectomy: preliminary experience with 5-aminolevulinic acid. Fukuhara H, Inoue K, Satake H, Tamura K, Karashima T, Yamasaki I, Tatsuo I, Kurabayashi A, Furihata M, Shuin T. Int J Urol. 2011 Aug;18(8):585-91. doi: 10.1111/j.1442-2042.2011.02789.x. Epub 2011 Jun 9.
Clinical experience with transurethral resection of bladder tumor (TUR-Bt) guided by photodynamic diagnosis (PDD). Inoue K, Kuno T, Fukuhara H, Hamaguchi T, Fukata S, Karashima T, Kamada M, Shuin T, Sakakura N, Kasahara K, Watanabe H, Kozai T, Yasuda M, Kataoka S, Tanimura M, Atsushi K, Furihata M. Nihon Hinyokika Gakkai Zasshi. 2009 Nov;100(7):661-70. Japanese.
Regulation of 5-aminolevulinic acid-mediated protoporphyrin IX accumulation in human urothelial carcinomas. Inoue K, Karashima T, Kamada M, Shuin T, Kurabayashi A, Furihata M, Fujita H, Utsumi K, Sasaki J. Pathobiology. 2009;76(6):303-14. doi: 10.1159/000245896. Epub 2009 Nov 30.
Mechanism of cell death by 5-aminolevulinic acid-based photodynamic action and its enhancement by ferrochelatase inhibitors in human histiocytic lymphoma cell line U937. Amo T, Kawanishi N, Uchida M, Fujita H, Oyanagi E, Utsumi T, Ogino T, Inoue K, Shuin T, Utsumi K, Sasaki J. Cell Biochem Funct. 2009 Dec;27(8):503-15. doi: 10.1002/cbf.1603.
Regulation of 5-aminolevulinic acid-dependent protoporphyrin IX accumulations in human histiocytic lymphoma U937 cells. Okimura Y, Fujita H, Ogino T, Inoue K, Shuin T, Yano H, Yasuda T, Inoue M, Utsumi K, Sasaki J. Physiol Chem Phys Med NMR. 2007;39(1):69-82.
Clinical experience with intravesical instillations of 5-aminolevulinic acid (5-ALA) for the photodynamic diagnosis using fluorescence cystoscopy for bladder cancer. Inoue K, Karashima T, Kamada M, Kurabayashi A, Ohtsuki Y, Shuin T. Nihon Hinyokika Gakkai Zasshi. 2006 Jul;97(5):719-29. Japanese.
業績 2017-2018
井上啓史、花崎和弘. レーザー施設紹介 「高知大学医学部附属病院 光線医療センター」 日レ医誌 第38巻, 第2号, p198, 2017
福原秀雄、井上啓史、並川努 杉本健樹、花﨑和弘、山本正樹、栗山元根、穴山貴嗣、渡橋和政、石元達士、中島英貴、佐野栄紀、川西裕、上羽哲也、佐藤隆幸、執印太郎. 第1章 光を活用した新しい診断技術の現状と高感度化 9節 泌尿器科領域における光を用いた診断と今後の早期、簡便、高感度化. 株式会社 技術情報協会 書籍 No.1912 「疾患・病態検査診断法の開発」 P27-30, (2017年9月)
並川努、杉本健樹、花﨑和弘、福原秀雄、井上啓史、山本正樹、栗山元根、穴山貴嗣、渡橋和政、石元達士、中島英貴、佐野栄紀、川西裕、上羽哲也、佐藤隆幸、執印太郎. 第1章 光を活用した新しい診断技術の現状と高感度化 5節 消化器科領域における光を用いた診断と今後の早期、簡便、高感度化. 株式会社 技術情報協会 書籍 No.1912 「疾患・病態検査診断法の開発」 P31-37, (2017年9月)
Namikawa T, Fujisawa K, Munekage E, Iwabu J, Uemura S, Tsujii S, Maeda H, Kitagawa H, Fukuhara H, Inoue K, Sato T, Kobayashi M, Hanazaki K.
Clinical application of photodynamic medicine technology using light-emitting fluorescence imaging based on a specialized luminous source.
Med Mol Morphol. 2018 Apr 4. doi: 10.1007/s00795-018-0190-2
並川努、宇都宮正人、津田祥、藤澤和音、宗景絵里、岩部純、上村直、金川俊哉、
辻井茂宏、前田広道、北川博之、福原秀雄、岡本健、井上啓史、小林道也、花﨑和弘
胃癌に対する5-アミノレブリン酸を用いた光力学的診断の有用性
高知県医師会医学雑誌,23(1):186-191、2018.
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